Faculty

Current Position
Professor & Director, Inst. of Public Health, National Yang Ming Chiao Tung UniversityProfessor, Department of Public Health, School of Medicine, College of Medicine, NYCU
Professor, Institute of Public Health, College of Medicine, NYCU
Deputy director, Center for Institutional Research and Data Analytics, NYCU
Director, Yang Ming Branch, Health and Welfare Data Science Center (HWDC), Ministry of
Health and Welfare, Taiwan
Joint appointments:
Master of Public Health program (MPH), College of Medicine, NYCU
International Health program (IHP), College of Medicine, NYCU
Institute of Environmental and Occupational Health Sciences, College of Medicine, NYCU
Institute of Food Safety and Health Risk Assessment, College of Pharmaceutical Sciences, NYCU
Master program in Transdisciplinary Long-term Care and Management, NYCU

Education

DrPH in Biostatistics, School of Public Health, Columbia University, New York, U.S.A.

Office
Room 207, 2nd Medical Building

Academic Degrees
Doctor of Public Health in Biostatistics, Columbia university

Experience
*National Yang Ming University (NYMU) and National Chiao-Tung University (NCTU) merged into National Yang Ming Chiao Tung University (NYCU) on 1st of February 1, 2021
Director, Master of Public Health (MPH) Program, College of Medicine, NYMU, 2019-2020
Chairman, Institute of Public Health, College of Medicine, NYMU, 2015-2019
Director, Department of Public Health and Medical Humanities, School of Medicine, College of Medicine, NYMU, 2015-2019
Director, Office of Institutional Research, NYMU, 2019-2021
Director, Biostatistical Consulting Center, NYMU, 2012-2017
Associate professor, Department of Public Health, School of Medicine, College of Medicine, NYMU, 2007-2013
Assistant Professor, Department of Public Health, School of Medicine, College of Medicine,NYMU, 2003-2007
Statistician, Northern Manhattan Stroke Study (PI: Dr. Ralph Sacco), Columbia-Presbyterian Medical Center, New York, New York, USA, 1996-2000
Lecturer, Department of Social Medicine, School of Medicine, Faculty of Medicine, National Yang-Ming University, 1989-2002 (1995- 2000 Doctorate studies in Columbia University, U.S.A.)

Research Interests

Statistical methods in epidemiologic and clinical studies, Environmental epidemiology, Infectious diseases surveillanceStatistical methods in epidemiologic and clinical studies
Risk assessment in population health

HONORS AND AWARDS

National Yang-Ming University School of Medicine Outstanding Teaching awards, 2008, 2019
National Science Council Research award, 2000
Distinction awarded to dissertation in School of Public Health, Columbia University, 2000 

IHP Thesis Advisee
1. Amadou Darboe. Effort-Reward Imbalance, Job Satisfaction & Self-rated Health among Healthcare Professionals in The Gambia. 2015 (Co-advisor with Dr. Kuo, Hsien-Wen)

 

Selected Publications (Peer review journal articles) 

*Correspondent, #Equal contribution

• Lan CF, Lin IF, Wang SJ. Fluoride in drinking water and the bone mineral density of women in Taiwan. Int J Epidemiol 1995 Dec;24(6):1182-7
• Sacco RL, Roberts K, Boden B, Gu Q, Lin IF, Kargman DE, Berglund L, Hauser WA, Shea S, Paik MC. Race-Ethnicity and Determinants of CarotidAtherosclerosis in a Multiethnic Population The Northern Manhattan Stroke Study. Stroke. 1997;28:929-935
• Kargman DE, Tuck C, Berglund L, Lin IF, Mukherjee RS, Thompson EV, Jones J, BodenAlbala B, Paik MC, Sacco RL. Lipid and lipoprotein levels remain stable in acute ischemic stroke: the Northern Manhattan Stroke Study. Atherosclerosis 1998 Aug;139(2):391-9
• Sacco RL, Gan R, Boden B, Lin IF, Kargman DE, Hauser WA, Shea S, Paik MC Leisure-time physical activity and ischemic stroke risk: the Northern Manhattan Stroke Study. Stroke 1998 Feb;29(2):380-7
• Mast H, Thompson JL, Lin IF, Hofmeister C, Hartmann A, Marx P, Mohr JP, Sacco RL. Cigarette smoking as a determinant of high-grade carotid artery stenosis in Hispanic, black, and white patients with stroke or transient ischemic attack. Stroke 1998 May;29(5):908-12
• Sacco RL,Elkind M, Boden B, Lin IF,Kargman DE, Hauser WA,Shea S,Paik MC. The protective effect of moderate alcohol consumption on Ischemic stroke. JAMA 1999;281:53-60
• Phillips GB, Tuck CH, Jing TY, Boden-Albala B, Lin IF, Dahodwala N, Sacco RL Association of hyperandrogenemia and hyperestrogenemia with type 2 diabetes in Hispanic postmenopausal women. Diabetes Care. 2000;23(1):74-9.
• Rundek T, Mast H, Hartmann A, Boden-Albala B, Lennihan L, Lin IF, Paik MC, Sacco RL Predictors of resource use after acute hospitalization: the Northern Manhattan Stroke Study. Neurology. 2000 Oct 24;55(8):1180-7.
• Elkind MS, Lin IF, Grayston JT, Sacco RL Chlamydia pneumoniae and the risk of first ischemic stroke : The Northern Manhattan Stroke Study. Stroke 2000;31(7):1521-5. (SCI)
• Paik MC, Sacco RL and Lin IF. Bivariate binary data analysis with missing outcomes. Biometrics 2000;56:1145-1156
• Ho SJ, Lin IF, Chuang ML, Lin CS, Lin MC, Tsao TCY. Comparison of lactate threshold using plasma and whole blood lactate during a ramppattern exercise in dyspneic patients. J. Thoracic Medicine. (In Chinese) 2001;16:80-88.
• Sacco RL, Benson RT, Kargman DE, Boden-Albala B, Tuck C, Lin IF, Cheng JF, Paik MC, Shea S, Berglund L. High-density lipoprotein cholesterol and ischemic stroke in the elderly: the Northern Manhattan Stroke Study. JAMA 2001; 285(21):2729-35
• Sacco RL, Boden-Albala B, Abel G, Lin IF, Elkind M, Hauser WA, Paik MC, Shea S. Raceethnic disparities in the impact of stroke risk factors: the northern Manhattan stroke study. Stroke 2001 32(8):1725-31
• Chuang ML, Lin IF, Wasserman K. The body weight-walking distance product as related to lung function, anaerobic threshold and peak in COPD patients. Respiratory Medicine 2001;95(7):618-26
• Lin IF, Paik MC. Matched case-control data analysis with selection bias. Biometrics
  2001;57:1106-1112
• Jacobs BS, Boden-Albala B, Lin IF, Sacco RL. Stroke in the young in the northern Manhattan
  stroke study. Stroke 2002;33(12):2789-983
• Chuang ML, Lin IF, Tsai YH, Vintch JRE, Pang LC. The utility of open lung biopsy in patients with diffuse pulmonary infiltrates as related to respiratory distress, its impact on decision making by urgent intervention, and the diagnostic accuracy based on the biopsy
  location. J Intensive Care Med 2003;18:21-28.
• Lin IF, Chuang ML, Liao YF, Chen NH, Li HY. Predicting effective continuous positive airway pressure in Chinese patients with obstructive sleep apnea syndrome. J. of the Formosan Medical Association. 2003;102:215-21
• Chuang ML, Lin IF, Vintch JRE. Comparison of estimated and measured maximal oxygen uptake during exercise testing in patients with chronic obstructive pulmonary disease. Internal Medicine Journal 2004;34(8):469-74.
• Chuang ML,Chuang DCC, Lin IF, Vintch JRE, Tsao TCC. Ventilation and Exercise Performance after Phrenic Nerve and Multiple Inter-costal Nerve Transfers for Avulsed Brachial Plexus Injury. Chest 2005;128:3434-3439
• Lin IF*, Lai MY, Chuang PH. Analysis of Matched Case-Control Data with Incomplete Strata: Applying Longitudinal Approaches. Epidemiology 2007;18(4):446-452. 
• Yu WC, Lin YP, Lin IF, Chuang SY, Chen CH. Effect of ramipril on left ventricular mass in normotensive hemodialysis patients. American J Kidney Disease. 2006;47(3):478-84.
• Chuang ML, Lin IF, Vintch JRE, Ho HJ, Chao SW, and Ker JJW. Significant exerciseinduced hypoxemia with equivocal desaturation in patients with chronic obstructive pulmonary disease (COPD). Internal Medicine Journal 2006;36(5)294-301
• Chuang SY, Chou P, Hsu PF, Cheng HM, Tsai ST, Lin IF, Chen CH. Presence and progression of abdominal obesity are predictors of future high blood pressure and hypertension. Am J Hypertens 2006;19(8):788-95
• Chou YJ, Huang N, Lin IF, Deng CY, Tsai YW, Chen LS, Lee CH. Do physicians and their relatives have a decreased rate of cesarean section? A 4-year population-based study in taiwan. Birth 2006;33(3):195-202
• Chuang ML, Lin IF, Vintch JRE, Liao YF. Predicting Continuous Positive Airway Pressure from a Modified Split-Night Protocol in Moderate to Severe Obstructive Sleep ApneaHypopnea Syndrome. Internal Medicine 2008; 47(18):1585-92
• Hsu PF, Yu WC, Lin IF, Lin YP, Chuang SY, Cheng HM, Chen CH. Differential effects of age on carotid augmentation index and aortic pulse wave velocity in end-stage renal disease patients. J Chin Med Assoc 2008; 71(4):166-173.
• Hwang SL, Hwang JH, Yang YT, Hsieh WA, Chang TC, Guo HR, Tsai MH, Tang JL, Lin IF*, Chang WP. Estimates of relative risks for cancers in a population post prolonged low dose-rate radiation exposure: a follow-up assessment from 1982 to 2005. Radiation Research 2008;170:143-148 (*Corresponding author)
• Liao YF, Lin IF. Dental arch relationships after two-flap palatoplasty in Taiwanese patients with unilateral cleft lip and palate. Int J Oral Maxillofac Surg. 2009; 38(11):1133-6
• Liao YF, Huang CS, Lin IF. Intraoral photographs for rating dental arch relationships in unilateral cleft lip and palate. Cleft Palate Craniofac J. 2009;46(4):415-9 
• Chan TC, Chen ML, Lin IF, Lee CH, Chiang PH, Wang DW, Chuang JH. Spatiotemporal analysis of air pollution and asthma patient visits in Taipei, Taiwan. Int J Health Geogr. 2009 May 7;8:26.
• Sun YF, Leu JD, Chen SM, Lin IF, Lee YJ. Results based on 124 cases of breast cancer and controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the
• MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer. BMC Cancer 2009, 9:13
• Leu JD, Lin IF, Sun YF, Chen SM, Liu CC, Lee YJ. Association between MDM2-SNP309 and hepatocellular carcinoma in Taiwanese population. World J Gastroenterol. 2009;15(44):5592-7
• Chuang ML, Lee CH, Lin IF. Using the Oxygen-Cost Diagram in Ramp-slope Selection for Dyspneic Patients. Internal Medicine 2010; 49: 1325-1332
• Boden-Albala B, Kargman DE, Lin IF, Paik MC, Sacco RL, Berglund L. Increased stroke risk and lipoprotein(a) in a multiethnic community: the Northern Manhattan Stroke Study. Cerebralvascular Diseases 2010;30(3):237-43
• Hsieh WA, Lin IF, Chang WP, Chen WL, Hsu YH, Chen MS. Lens opacities in young individuals long after exposure to protracted low-dose-rate γradiation in 60CO-contaminated building in Taiwan. Radiation Research 2010;173(2):197-204
• Leu JD, Wang CY, Tsai HY, Lin IF, Chen RC, Lee YJ. Involvement of p53 R72P polymorphism in the association of MDM2-SNP309 with breast cancer. Oncology Reports. 2011 Jun;25(6):1755-63.
• Chuang PH, Chuang JH, Lin IF*. A Dynamic Estimation of the Daily Cumulative Cases during Infectious Disease Surveillance: Application to Dengue Fever. BMC Infectious diseases 2010;10:136 (*Corresponding author)
• Yen PN, Yang CC, Chang WP, Hwang JS, Lee HC, Kuo KL, Lin IF*. Perception of quality of life of a cohort population years after relocation from previous low-dose radiation exposure in Co-60 contaminated buildings in Taiwan. International Journal of Radiation Biology
  2011;85(5):453-460 (*Corresponding author)
• Chuang ML﹟, Lin IF﹟, Vintch JRE, Tien EH. Using Statistical Techniques to Predict Dynamic Arterial PCO2 in COPD Patients during Maximum Exercise. Respiratory Care 2012;57(7):1106 –1114 (﹟ Equal contribution)
• Yu WC, Lin YP, Chuang SY, Lin IF, Chen CH. Cardiovascular determinants of prognosis in normotensive hemodialysis patients. BMC Nephrol. 2012 Sep 20;13:115 
• Chuang CM﹟, Lin IF﹟, Horng HC, Hsiao YH, Shyu IL, Chou P. The impact of gestational diabetes mellitus on postpartum urinary incontinence: a longitudinal cohort study on singleton pregnancies. BJOG. 2012 Oct;119(11):1334-43 (﹟Equal contribution)
• Lee PW, Ji DD, Liu CT, Rampao HS, do Rosario VE, Lin IF, Shaio MF. Application of loopmediated isothermal amplification for malaria diagnosis during a follow-up study in São Tomé. Malaria J. 2012 Dec 6;11:408
• Chen CY, Lin IF, Huang SL, Tsai TI, Chen YY. Disposable income with tobacco smoking among young adolescents: a multilevel analysis. Journal of Adolescent Health. 2013 Jun;52(6):724-30
• Lin YS, Lin IF, Yen YF, Lin PC, Shiu YC, Hu HY, Yang YP.Impact of an antimicrobial stewardship program with multidisciplinary cooperation in a community public teaching hospital in Taiwan. Am J Infect Control. 2013 Nov;41(11):1069-72
• Huang SL, Lin IF, Chen CY,Tsai TI. Impact of tobacco control policies on adolescent smoking: findings from Global Youth Tobacco Survey in Taiwan. Addiction. 2013 Oct;108(10):1829-35
• Yen PN, Yang CC, Chang WP, Wang JD, Hwang JS, Chang TC, Kuo KL, Lin IF*. Late effects on the health-related quality of life in a cohort population decades after environmental radiation exposure. International Journal of Radiation Biology 2013; Aug;89(8):639-44
  (*Corresponding author)
• Lin IF*,Chang WP, Liao YN. Shrinkage Methods Enhanced the Accuracy of Parameter Estimation Using Cox models with Small Number of Events. J Clinical Epidemiology 2013; Jul;66(7):743-51 (*Corresponding author)
• Chuang ML, Lin IF. Clinical characteristics and lung function in chronic obstructive pulmonary disease complicated with impaired peripheral oxygenation. Internal and Emergency Medicine. 2013.Sept;9(6):633-40 
• Chuang ML, Lin IF, Chen SP. Kinetics of Changes in Oxyhemoglobin Saturation During Walking and Cycling Tests in COPD. Respiratory Care. 2014 ; Mar;59(3):353-62.
• Kang SC, Pai FT, Hwang SJ, Tsao HM, Liou DM, Lin IF. Noncancer hospice care in taiwan: a nationwide dataset analysis from 2005 to 2010. J Palliat Med. 2014;Apr;17(4):407-14 
• Yen PN﹟, Lin IF﹟, Chang WP, Wang JD, Chang TC, Kuo KL, Hwang JS, Liu IC, Chen YT, Yang CC. Risk factors of depression after prolonged low-dose rate environmental radiation exposure. Int J Radiat Biol. 2014;Aug;11:1-8 (﹟Equal contribution)
• Hsu LC, Chen YJ, Hsu FK, Huang JH, Chang CM, Chou P, Lin IF*, Chang FY. The incidence of Japanese encephalitis in Taiwan--a population-based study. PLoS Negl Trop Dis. 2014; Jul;24;8(7):e3030 (*Corresponding author)
• Yen YF, Hu HY, Lin IF , Lai YJ, Su VY, Pan SW, Ting WY, Su WJ. Associations of Metabolic Syndrome and its Components with Mortality in the Elderly: A Cohort Study of 73,547 Taiwanese Adults. Medicine. 2015; Jun;94(23):e956
• Lin YT, Yen CH, Chen HL, Liao YJ, Lin IF , Chen M, Lan YC, Chuang SY, Hsieh SL, Chen YM. The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients. J Formos Med Assoc. 2015; Jun;114(6):498-503
• Duong VT, Lin IF, Sorensen K, Pelikan JM, Van Den Broucke S, Lin YC, Chang WP. Health literacy in Taiwan: a population-based study. Asia Pac J Public Health. 2015;Jul;27(8):871- 80.
• Chuang ML, Wu TC, Wang YT, Wang YC, Tsao TC, Wei JC, Chen CY, Lin IF. Adjunctive Treatment with Rhodiola Crenulata in Patients with Chronic Obstructive Pulmonary DiseaseA Randomized Placebo Controlled Double Blind Clinical Trial. PLoS One. 2015; Jun22;10(6):e0128142
• Wang MC, Lin IF*. Managing nonignorable missing data with clustered multinomial Responses. Statistical Modelling. 2015;15(6):548-563 (*Corresponding author)  
• Chuang ML, Lee CY, Chen YF, Huang SF, Lin IF. Revisiting unplanned endotracheal extubation and disease severity in intensive care units. Plos One. 2015;Oct10(10):e0139864.
• Chuang ML, Lin IF, Lee CY. Clinical assessment tests in evaluating patients with chronic obstructive pulmonary disease: a cross-sectional study. Medicine. 2016 Nov;95(47):e5471.
• Darboe A, Lin IF, Kuo HW. Effort-reward imbalance and self-rated health among Gambian healthcare professionals. BMC Health Serv Res. 2016 Apr11;16(1):125
• Yen YF, Hu HY, Lee YL, Ku PW, Lin IF, Chu D, Lai YJ. Obesity/overweight reduces the risk of active tuberculosis: a nationwide population-based cohort study in Taiwan. Int J Obes. 2017 Jun;41(6):971-975
• Chuang ML, Lin IF, Huang SF, Hsieh MJ. Patterns of oxygen pulse curve in response to incremental exercise in patients with chronic obstructive pulmonary disease - an observational study. Sci Rep 2017 Sep 7; 7(1):10929 
• Hsieh WA#, Lin IF#, Ho JH, Chang PW. 30 years follow-up and increased risks of breast cancer and leukaemia after long-term low dose-rate radiation exposure. British J Cancer 2017 Dec 5; 117(12):1883-1887 [Epub 2017 Oct 3] ( ﹟Equal contribution)
• Duong TV, Sorensen K, Pelikan JM, Van den Broucke S, Lin IF, Lin YC, Huang HL, Chang
  PW. Health-related behaviors moderate the association between age and self-reported health literacy among Taiwanese women. Women Health 2018 Jul;58(6):632-646. Epub 2017 Jul 6 66. Hsieh WA# , Lin IF# , Ho JH, Chang PW. Reply to ‘Comment on ‘30 years follow-up and increased risks of breast cancer and leukaemia after long-term low dose-rate radiation exposure.’’ British J Cancer 2018;Mar;118(5):e10[Epub 2018 Feb 13] (﹟ Equal contribution)
• Lee WJ, Liao YC, Wang YF, Lin IF,Wang SJ; Fuh JL. Plasma MCP-1 and cognitive decline in patients with Alzheimer’s disease and mild cognitive impairment: a two-year follow-up study. Sci Rep 2018 Jan 19; 8(1):1280
• Chuang ML, Hsieh MJ, Wu TC, Lin IF. Developing a new marker of dynamic hyperinflation in patients with obstructive airway disease – an observational study. Sci Rep 2019 May 17; 9(1):7514
• Tsai TH, Huang N, Lin IF, Chou YJ. Variation in the 11-year trajectories of medical care seeking behaviors in diabetes patients under a single payer system: persisting gaps to be fillled. BMC Health Serv Res. 2019 Aug19;19(1):580
• Chuang ML, Lin IF, Hsieh MJ. More impaired dynamic ventilator muscle oxygenation in congestive heart failure than in chronic obstructive pulmonary disease. J Clin Med 2019 Oct 7; 8(10):1641
• Wang MC, Hu HY, Lin IF, Chuang JT. Plasma lipid concentrations and survival in geriatric population: A retrospective cohort study. Medicine. 2019 Dec;98(49)e18154 
• Chuang ML, Lin IF. Investigating the relationships among lung function variables in chronic 
• Duong TV, Aringazina A, Kayupova G, Nurjanah, Pham TV, Pham KM, Truong TQ, Nguyen KT, Oo WM, Su TT, Majid HA, Sorensen K, Lin IF, Chuang Y, Yang SH, Chang PWS. Development and validation of a new short-form health literacy instrument (HLS-SF12) for the general public in six Asian countries. Health Lit Res Pract 2019 Apr 10:3(2):e91-e102
• Tsai TH, Huang N, Lin IF, Chou YJ. Severe diabetes complications among patients with diabetes with regular follow-up: Does care setting matter? J Eval Clin Pract. 2020 Aug;26(4):1212-1219
• Chiu SJ, Lin IF, Chou YT, Chien LY. Family quality of life among Taiwanese children with developmental delay before and after early intervention. J Intellect Disabil Res. 2020 Aug;64(8):589-601
• Cheng HY, Wu YC, Lin MH, Liu YL, Tsai YY, Wu JH, Pan KH, Ke CJ, Chen CM, Liu DP, Lin IF, Chuang JH. Applying machine learning models with an ensemble approach for accurate real-time influenza forecasting in Taiwan: development and validation study. J Med Internet Res. 2020 Aug 5;22(8):e15394 
• Chuang ML, Hsieh BYT, Lin IF. Resting Dead Space Fraction as Related to Clinical Characteristics, Lung Function, and Gas Exchange in Male Patients with Chronic Obstructive Pulmonary Disease. International Journal of General Medicine. 2021 2021:14 169-177
• Chuang YH, Lin IF, Lao XQ, Lin CQ, Chan TC. The Association Between Renal Function
• Decline and the Incidence of Urothelial Carcinoma: A 16-year Retrospective Cohort Study in Taiwan. European Urology Open Science. 2021 27(2021)1-9
• Chuang ML, Hsieh BT, Lin IF. Prediction and types of dead-space fraction during exercise in male chronic obstructive pulmonary disease patients. Medicine 2022;101:6(e28800).
• Cheng CY, Ku SY, Lin YC, Chen CP, Cheng SH, Lin IF*. Incidence and risk factors of reinfection with HCV after treatment in people living with HIV. Viruses 2022, 14, 439.
• Estrada JA, Cheng CY*, Ku SY, Hu HC, Yeh HW, Lin YC, Chen CP, Cheng SH, Janssen R, Lin IF*. An immune-bridging study to evaluate the neutralizing antibody titer in adults immunized with two doses of either ChAdOx1-nCov-19 (AstraZeneca) or MVC-COV1901.
  Vaccines 2022, 10, 655. 
• Masina H V, Lin IF, Chien LY*. Impact of the COVID-19 Pandemic on Tuberculosis Case Notification and Treatment Outcomes in Eswatini. Int J Public Health. 2022, 67: 1605225.   
• Chen YJ, Lin IF, Chuang JH, Huang HL, Chan TC*. Influenza vaccination is associated with a reduced risk of invasive aspergillosis in high-risk individuals in Taiwan: a population-based cohort study. Emerging Microbes & Infections. 2022(Accepted)

OTHER PUBLICATIONS

• Lin IF. A conversation with Kung-Yee Liang. ICSA Bulletin July 2016 Vol28/2:97-102
  https://icsaimage.files.wordpress.com/2016/07/icsa_bulletin_july2016_online.pdf
  

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