Current Position

1. Assistant Professor, Department of Tropical Medicine, National Yang Ming Chiao Tung University

2. Assistant Professor, Institute of Public Health and Department of Social Medicine, National Yang Ming Chiao Tung University

Office

Room 611, Shou-Ren Building

Academic Degree

PhD-Graduate Institute of Life Science, National Defense Medical Center, Taiwan

MS-Graduate Institute of Biomedical Technology, Taipei Medical University, Taiwan

BS-School of Medical Laboratory Science and Biotechnology, Taipei Medical University, Taiwan

Experience

Postdoctoral Research Fellow-Oct 2020 - July 2021

School of Medical Laboratory Science and Biotechnology, Taipei Medical University

Postdoctoral Research Fellow-Jun 2019 - July 2020

One Health Research Center, National Yang-Ming University             

Postdoctoral Research Fellow-Feb 2013 - Feb 2019                                                           

Genomics Research Center/Agriculture Biotechnology Research Center, Academia Sinica 

Specialty

Autophagy, Tumor-immune regulation, Signal transduction and Autophagy-based drugs screening

Research Interests

1. Parasitic infection and cancer development
2. Autophagy and tumor immune microenvironment
3. Autophagy-based drugs development and immunotherapy

Course and lecture

1. Infection and Applied Tumor Immunology

2. Introduction to Tropical Medicine (Topic of HIV/AIDS)

Selected Publications
Journal Publications-

1. Li CH, Liao CC*. The metabolism reprogramming of microRNA Let7-mediated glycolysis contributes to autophagy and tumor progression. International Journal of Molecular Sciences. 2022 Jan; 23(1): 113. 

2. Liao CC* Ho MY, Liang SM, Liang CM. Autophagic degradation of SQSTM1 inhibits ovarian cancer motility by decreasing DICER1 and AGO2 to induce MIRLET7A-3P. Autophagy. 2018 Jul;14(12):2065-2082

3. Chen TA, Liao CC*, Cheng YC, Chen YP, Hsu YF, Liang CM, Liang SM. Stimulation of proliferation and migration of mouse macrophages by type B CpG-ODNs is F-spondin and IL-1Ra dependent. PLoS One. 2015 Jun 4;10(6):e0128926. 

4. Liao CC*, Ho MY, Liang SM, Liang CM. Recombinant protein rVP1 upregulates BECN1-independent autophagy, MAPK1/3 phosphorylation and MMP9 activity via WIPI1/WIPI2 to promote macrophage migration. Autophagy. 2013 Jan;9(1):5-19. 

5. Chen BC, Kang JC, Lu YT, Hsu MJ, Liao CC*, Chiu WT, Yeh FL, Lin CH. Rac1 regulates peptidoglycan-induced nuclear factor-kappaB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages by activating the phosphatidylinositol 3-kinase/Akt pathway. Mol Immunol. 2009 Mar;46(6):1179-88.

6. Chen BC, Liao CC*, Hsu MJ, Liao YT, Lin CC, Sheu JR, Lin CH. Peptidoglycan-induced IL-6 production in RAW 264.7 macrophages is mediated by cyclooxygenase-2, PGE2/PGE4 receptors, protein kinase A, I kappa B kinase, and NF-kappa B. J Immunol. 2006 Jul 1;177(1):681-93.

Technology transfer-

Liao CC*, Liang SM, Liang CM. Becn1 stable knockdown RAW264.7 cell line. Academia Sinica Technology transfer, 2019 Dec. Docket Number: 28T-1080725-1N