Faculty

Current Position

Professor, Department of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University

 

Office

Room 320, 3F, Biomedical Science and Engineering Building

 

Academic Degrees

Ph.D., Institute of Microbiology and Immunology, NYCU
B.S., Department of Medical Technology, Kaohsiung Medical University

 
Experience

Professor/Director, Department of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University

Visiting Scholar, Faculty of Health, Education and Life Sciences, Birmingham City University, UK
Visiting Scholar, Department of Oncology, University of Sheffield, UK
Visiting Scholar, Erasmus Mundus International Master Program, Encole Normale Supreme du Cachan Paris, France
Professor/Director, School of Medical Technology and Biotechnology, Chung Shan Medical University

 

Specialty

Molecular Diagnostics, Metabolic Syndrome, Diabetes Mellitus, Microbiology/Immunology

 

Research Interests

Diabetes mellitus, metabolic syndrome, obesity, immunology, molecular diagnostics

 

Selected Publications

• Chang YH, Yang HJ, Chen HW, Hsiao CW, Hsieh YC, Chan YW, Chang, SW, Hwang WL, Chen WS, Cheng HH, et al. Characterization of collapsin response mediator protein 2 in colorectal cancer progression in subjects with diabetic comorbidity. Cells 2022; 11, 727. 
  
• Chang YH^#, Tsai JN^#, Chang SW, Hsu WT, Yang CP, Hsiao CW, Shiau MY. Regulation of adipogenesis and lipid deposits by collapsin response mediator protein 2. International Journal of Molecular Sciences 2020; 21, 2172.
• Shiau MY, Chuang PH, Yang CP, Hsiao CW, Chang SW, Chang KY, Liu TM, Chen HW, Chuang CC, Yuan SY, and Chang YH*. Mechanism of interleukin-4 reducing lipid deposit by regulating hormone-sensitive lipase. Scientific Reports 2019; 9: Article number: 11974. 
• Chang YH^#, Tsai JN^#, Chen TZ, Ho KT, Cheng HY, Hsiao CW, and Shiau MY*. Interleukin-4 promotes myogenesis and boosts myocyte insulin efficacy. Mediators of Inflammation 2019; 2019: Article ID 4182015.
•  Yang CP^#, Shiau MY^#, Lai YR, Ho KT, Hsiao CW, Chen CJ, Lo YL, and Chang YH*. Anti-inflammatory cytokine interleukin-4 boosts insulin-induced energy deposits by enhancing glucose uptake and lipogenesis in hepatocytes. Oxidative Medicine and Cellular Longevity 2018, Article ID 6923187.  
• Shiau MY, Lee PS, Huang YJ, Yang CP, Hsiao CW, Chang KY, Chen HW, Chang YH*. Role of PARL-PINK1-Parkin pathway in adipocyte differentiation. Metabolism 2017; 72: 1-17.
• Tsao CH, Shiau MY, Chuang PH, Chang YH*, Hwang J. Interleukin-4 regulates lipid metabolism by inhibiting adipogenesis and promoting lipolysis. Journal of Lipid Research 2014;55:385-397.
• Chang YH, Ho KT, Lu SH, Huang CN and Shiau MY^#. Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4. International Journal of Obesity 2012;36:993-998.