Faculty

Current Position 

Director, Department of Pharmacy, National Yang Ming Chiao Tung University, Taiwan

Professor, Institute of Pharmacology, National Yang Ming Chiao Tung University, Taiwan

Joint Appointment Research Fellow, Department of Medicine Research, Taipei Veterans General Hospital, Taiwan

Office

Rm 702, Shou-Ren Building

Academic Degrees

Ph.D. Institute of Pharmacy, Colorado State University, USA (1989-1992)

MS. Institute of Pharmacology, National Taiwan University, Taiwan (1982-1984)

Bachelor. Department of Pharmacy, National Taiwan University, Taiwan (1978-1982)

Experience

Supervisor, Faculty of Pharmacy, National Yang Ming University, Taiwan (2015/08 till now)

Professor, Institute of Pharmacy, National Yang-Ming  University, Taiwan (2016/08 till now)

Director, Institute of Pharmacology, National Yang-Ming University, Taiwan (2008/08-2014)

Professor, Department of Physiology, National Yang-Ming University, Taiwan (2005/08-2008/07)

Joint Appointment Research Fellow, Department of Medicine Research, Taipei Veterans General Hospital, Taiwan (2005/08 till now)

Research fellow, Department of Medicine Research, Taipei Veterans General Hospital, Taiwan (2004-2005/07)

Adjunct associate professor, Institute of Physiology, National Yang-Ming University, Taiwan (1998-2005/02)

Associate Research Fellow, Department of Medicine Research, Taipei Veterans General Hospital, Taiwan (1996-2004)

Postdoctoral Research Fellow, Institute of Biomedical Sciences, Academia Sinica, Taiwan (1993/10-1996/10) 

Visiting postdoctoral researcher fellow, National Institutes of Health, USA (1992/08-1993/09)

Specialty

Neuropharmacology, nerve regeneration, translational medical research

Research Interests

1. Pathophysiology of CNS neurodegenerative diseases

2.Transitional studies of neuroprotective strategies 

Selected Publications

• T Ho WC, Hsu CC, Huang HJ, Wang HT, Lin AM*.. Anti-inflammatory Effect of AZD6244 on Acrolein-Induced Neuroinflammation. Mol Neurobiol. 2020 Jan;57(1):88-95 
• Liu YL, Hsu CC, Huang HJ, Chang CJ, Sun SH, Lin AM*.. Gallic Acid Attenuated LPS-Induced Neuroinflammation: Protein Aggregation and Necroptosis. Mol Neurobiol. 2020 Jan;57(1):96-104. 
• Chen YJ, Hsu CC, Shiao YJ, Wang HT, Lo YL*, Lin AMY*. Anti-inflammatory effect of afatinib (an EGFR-TKI) on OGD-induced neuroinflammation. Sci Rep. 2019 Feb 21;9(1):2516. doi: 10.1038/s41598-019-38676-7. (IF=4.011; 15/69 Integrative & Complementary Medicine)
• Hong ST, Lin H, Wang CS, Chang CH, Lin AM, Yang JC, Lo YL*. Improving the anticancer effect of afatinib and microRNA by using lipid polymeric nanoparticles conjugated with dual pH-responsive and targeting peptides. J Nanobiotechnology. 2019 Aug 19;17(1):89. doi: 10.1186/s12951-019-0519-6. (IF= 5.345, 19/162 biotechnology and applied microbiology)
• Wei-Zhong Zhao, Hsiang-Tsui Wang, Hui-Ju Huang, Yu-Li Lo*, Anya Maan-Yuh Lin*. Neuroprotective effects of baicalein on acrolein-induced neurotoxicity in the nigrostriatal dopaminergic system of rat brain. Mol Neurobiol. 2018 Jan. doi: 10.1007/s12035-017-0725-x. [Epub ahead of print (IF=6.190; 25/259 Integrative & Complementary Medicine). 
• Huang HJ, Wang YT, Lin HC, Lee YH*, Lin AMY*. Soluble Epoxide Hydrolase Inhibition Attenuates MPTP-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System: Involvement of α-Synuclein Aggregation and ER Stress. Mol Neurobiol. 2018 jan. doi: 10.1007/s12035-017-0726-9. [Epub ahead of print] 
• Wang YT, Lin HC, Zhao WZ, Huang HJ, Lo YL, Wang HT*, Lin AMY*. Acrolein acts as a neurotoxin in the nigrostriatal dopaminergic system of rat: involvement of α-synuclein aggregation and programmed cell death. Sci Rep. 2017 Apr 12; 7:45741. doi: 10.1038/srep45741. (IF=4.259; 10/64 Integrative & Complementary Medicine) 
• Hung KC, Huang HJ, YT Wang, Lin AMY*. Baicalein inhibits MPP+-induced neurotoxicity involving synuclein, aggregation, inflammation activation and apoptosis. J Ethnopharmacology 2016 ;194:522-529 (IF=3.055; 2/24 Integrative & Complementary Medicine)