Faculty

Current Position

Associate Professor, Institute of Food Safety and Health Risk Assessment, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University

Education 

2005-2010  Doctor of Philosophy in Toxicology

Institute of Toxicology, College of Medicine, National Taiwan University

Dissertation title: “Effects of Oxysterols on Atherosclerosis”

Advisor: Professor Jaw-Jou Kang

2004-2005  Master Student

Institute of Toxicology, College of Medicine, National Taiwan University

1999-2004  Bachelor of Science in Agriculture

Department of Entomology, National Taiwan University

Work Experience

2022 Aug-present.  Full-Time Associate Professor
Institute of Food Safety and Health Risk Assessment, School of Pharmaceutical Sciences, National Yang Ming Chiao Tung University

2020 Aug-2022 Jul.  Full-Time Assistant Professor

Institute of Food Safety and Health Risk Assessment, School of Pharmaceutical Sciences, National Yang-Ming University

2018 Feb.- 2020 Jul.  Project Assistant Professor 

Institute of Food Safety and Health Risk Assessment, School of Pharmaceutical Sciences, National Yang-Ming University

2019 Jul. – Oct.  Visiting Scholar

Department of Environmental Medicine, New York University Langone Medical Center

2017-2018  Postdoctoral Research Fellow 

School of Pharmacy, Taipei Medical University

2011-2017  Postdoctoral Research Fellow

Institute of Toxicology, College of Medicine, National Taiwan University

Previous and Current Research

1. Ministry of Science and Technology, Taiwan, R.O.C.

2017-present  Projects: Investigation of PAHs, AhR and nano particles: toxicological perspectives. (Principle Investigator)

2. Industry-University Cooperative Research 

2010- present  Researcher and Principle Investigator of multiple industry-university cooperative research projects conducting non-GLP toxicity tests among various health foods.

Future Research

Application of intestinal organoid culture model on toxicological assessment among PAHs.

Exploring the microbiota's role in mutation of colorectal cancer.

Health foods development.

Publication List

1. Chiang CF*, Liao PL*, Hsu KC, Shen JY, Lin JT and Yang DJ. Establishment of optimal QuEChERS conditions of various food matrices for rapid measurement of heterocyclic amines in various foods. FOOD CHEMISTRY 2022; 380 (132184).
2. Chiang CF*, Liao PL*, Hsu KC, Chang CC, Lin JT, and Yang DJ. Establishment of an appropriate method for determining multiple heterocyclic amines in soy products processed with various methods. Food Chemistry 2022; 375 (131905).
3. Chan YJ, Liao PL, Tsai CH, Cheng YW, Lin FL, Ho JD, Chen CY, Li CH. Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation. Particle and Fibre Toxicology 2021; 18(1):4
4. Tsai CH, Fang TC, Liao PL, Liao JW, Chan YJ, Cheng YW, Li CH.. The Powdered Root of Eurycoma longifolia Jack Improves Beta-Cell Number and Pancreatic Islet Performance through PDX1 Induction and Shows Antihyperglycemic Activity in db/db Mice. Nutrients 2020; 16;12(7):2111.
5. Hsu HL, Liao PL, Cheng YW, Huang SH, Wu CH, Li CH, Kang JJ. Chloramphenicol Induces Autophagy and Inhibits the Hypoxia Inducible Factor-1 Alpha Pathway in Non-Small Cell Lung Cancer Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019; 20(1):pii: E157.
6. Liao PL, Huang SH, Hung CH, Huang WK, Tsai CH, Kang JJ, Wang HP, Cheng YW. Efficacy of Azatyrosine-Phenylbutyric Hydroxamides, a Histone Deacetylase Inhibitor, on Chemotherapy-Induced Gastrointestinal Mucositis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019; 20(2):pii: E249.
7. Tse LS, Liao PL, Tsai CH, Li CH, Liao JW, Kang JJ, Cheng YW. Glycemia Lowering Effect of an Aqueous Extract of Hedychium coronarium Leaves in Diabetic Rodent Models. Nutrients 2019; 11(3):pii: E629 (SCI). 
8. Chang YL, Lin JT, Lin HL, Liao PL, Wu PJ, Yang DJ. Phenolic compositions and antioxidant properties of leaves of eight persimmon varieties harvested in different periods. FOOD CHEMISTRY 2019; 289:74-83 (SCI). 
9. Lin JT, Chang YY, Chen YC, Liao PL, Yang DJ. Litchi (Litchi chinensis Sonn) flower proanthocyanidin fraction exhibited protective efficacy to suppress nickel-induced expression for vascular endothelial growth factor in HepG2 cells. JOURNAL OF FOOD BIOCHEMISTRY 2019; 43(7):e12882 (SCI).
10. Chen CY*, Liao PL*, Tsai CH, Chan YJ, Cheng YW, Hwang LL, Lin KH, Yen TL, Li CH. Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity. Particle and Fibre Toxicology 2019; 16(1):37 (SSCI). 
11. Tsai CH, Li CH, Liao PL, Chang YW, Cheng YW, Kang JJ. Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCα-mediated AHR-HDAC interactions. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2019; 1867(2):118564 (SCI).
12. Liao PL; Wu CC.; Chen TY.; Tsai YC.; Peng WS.; Yang DJ.; Kang, JJ.. Toxicity Studies of Lactobacillus plantarum PS128TM Isolated from Spontaneously Fermented Mustard Greens. foods 2019; 8(12):pii: E668.
13. Liao PL, Li CH, Tse LS, Kang JJ, Cheng YW. Safety assessment of the Cistanche tubulosa health food product MemoregainR: Genotoxicity and 28-day repeated dose toxicity test. FOOD AND CHEMICAL TOXICOLOGY 2018; 118:581-588 (SCI). 
    *Both authors contributed equally.